Clinical Group Genetics and Stem Cell Group Endophenotype Group Endophenotypes are measurable and heritable traits or behaviors linked to a disorder, that sit between the genetic factors and the observable symptoms of the condition. Psychiatric disorders are increasingly viewed as neurodevelopmental disorders, which are influenced by genetic, epigenetic & environmental factors. These clues offer insights into genetic underpinnings of these disorders. Utilising endophenotypes derived from various assessments like neuroimaging can enhance the reliability of research on brain function. Dr. John P. John Professor, Department of Psychiatry Dr. Venkatasubramanian Ganesan Professor, Department of Psychiatry Dr. Jitender Saini Professor, Department of Neuro Imaging & Interventional Radiology Dr Bharath Holla Associate Professor, Department of Psychiatry Dr. Sreeraj V S Associate Professor, Department of Psychiatry Affiliated Labs and Centre ADBS Neuroimaging Centre (ANC) Centre for Brain Mapping (CBM) Translational Psychiatry Lab (TransPsych) Multi-modal Brain Imaging Analysis Lab (MBIAL) Facilities Eye Tracking Functional Near-Infrared Spectroscopy (fNIRS) MRI Scanner Philips Ingenia 3.0T CX MRI EEG Featured Publications Parekh P, Vivek Bhalerao G; ADBS consortium, John JP, Venkatasubramanian G. Sample size requirement for achieving multisite harmonization using structural brain MRI features. Neuroimage. 2022;264:119768. doi:10.1016/j.neuroimage.2022.119768 Lakkireddy SP, Balachander S, Dayalamurthy P, et al. Neurocognition and its association with adverse childhood experiences and familial risk of mental illness. Prog Neuropsychopharmacol Biol Psychiatry. 2022;119:110620. doi:10.1016/j.pnpbp.2022.110620 Bhalerao GV, Parekh P, Saini J, Venkatasubramanian G, John JP; ADBS consortium. Systematic evaluation of the impact of defacing on quality and volumetric assessments on T1-weighted MR-images. J Neuroradiol. 2022;49(3):250-257. doi:10.1016/j.neurad.2021.03.001 Parekh P, Bhalerao GV, Rao R, et al. Protocol for magnetic resonance imaging acquisition, quality assurance, and quality check for the Accelerator program for Discovery in Brain disorders using Stem cells. Int J Methods Psychiatr Res. 2021;30(3):e1871. doi:10.1002/mpr.1871 Holla B, Dayal P, Das A, et al. Transdiagnostic neurocognitive endophenotypes in major psychiatric illness. medRxiv (Cold Spring Harbor Laboratory). February 2020. doi:10.1101/2020.02.14.20022863

Digital Resources Select & de-select type of resource Article Book Brochure Event Pages Games & Activities Infographic Video Webinar Select & de-select target audience General Public Patients and Families/Caregivers Researchers Students Information about Psychiatric Disorders Infographic Ancestry Bingo Games & Activities Brain Bridge Talks | Cellular models to study the origins of schizophrenia Webinar Brain Bridge Talks | Imaging Cognition to Investigate Psychosis by Professor Sagnik Bhattacharyya Webinar Brain Bridge Talks | Monoamines, Mitochondria and Mood by Dr Vidita Vaidya Webinar Brain Bridge Talks | Neuroimaging for Non-Invasive Therapeutics in Severe Mental Illnesses by Prof Lena Palaniyappan Webinar Brain Bridge Talks | The Neuroscientist's Guide to Schizophrenia by Dr. Jens Hjerling-Leffler Webinar Brain Bridge Talks | Unraveling the complexity using genetically diverse human cellular models Webinar Brain Bridge Talks | Unveiling Minds - Genetic Insights and Cellular Mechanisms Webinar Centre for Brain & Mind Brochure Brochure DNA Bracelet Cards Games & Activities E-Book | Mind the Gap Book FAQ - Common Stigmas in Bipolar Disorder Video FAQ - Common Stigmas in Bipolar Disorder (Tamil) Video FAQ - Dealing with Suicidal Thoughts Video FAQ - Dealing with Suicidal Thoughts (Hindi) Video FAQ - Dementia Awareness & Public Health Initiatives Video FAQ - How to Seek Help For Addiction Video FAQ - Is Addiction A Disease? Video FAQ - Living a Healthy Life with Bipolar Disorder Video FAQ - Living a Healthy Life with Bipolar Disorder (Tamil) Video FAQ - Loneliness & Dementia Video FAQ - Suicide Awareness Video FAQ - Suicide Awareness (Hindi) Video FAQ - Supporting Dementia Caregivers Video Load More Useful Links Accelerator Program for Discovery in Brain Disorders (ADBS) Wellcome Collection Human Brain Project Big Brain RIKEN Center for Brain Science (CBS) Simons Center for the Social Brain BRAIN Initiative UK Biobank Psychiatric Genomics Consortium International Consortium on Lithium Genetics (ConLiGen) Allen Brain Map cVEDA Project A-BIG-NET IC-MAGIC

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