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Facilities Clinical and Endophenotype Stem Cell Laboratory Molecular Genetics Laboratory Bioinformatics Stem Cell Laboratory Cell culture facility (80 m²) 1 A dedicated, sterile, air-flow controlled workspace for culture of primary and stem cells Biosafety Cabinets 4 Provide a sterile, air-flow controlled work environment for cell culture CO₂ Incubators 6 Provide a controlled environment to grow cells Fluorescence Microscopes 2 Used to visualise fluorescently labelled cells Phase-contrast Microscopes 2 Used to image live, unstained cells Neon Electroporator 1 Allows gene delivery via electroporation Amaxa Nucleofector 1 High-efficiency nucleic acid transfection Heated Incubators 3 Temperature-controlled storage/growth LN₂ Cryotanks 5 Long-term cryogenic cell storage Ultra-low Freezers (−80°C) 6 Biobanking at ultra-low temperatures −30°C Freezers 4 Medium-term sample storage Refrigerators 2 Sample and reagent storage High-content Imaging System 1 Automated, high-throughput cell imaging Autoclave 1 Equipment & media sterilization Spectrophotometer 1 Sample absorbance/concentration measurement Clinical and Endophenotype Facilities Eye Tracking Functional Near-Infrared Spectroscopy (fNIRS) Magnetic resonance imaging Philips Ingenia 3.0T CX MRI Electroencephalography

Clinical Group Genetics and Stem Cell Group Endophenotype Group Endophenotypes are measurable and heritable traits or behaviors linked to a disorder, that sit between the genetic factors and the observable symptoms of the condition. Psychiatric disorders are increasingly viewed as neurodevelopmental disorders, which are influenced by genetic, epigenetic & environmental factors. These clues offer insights into genetic underpinnings of these disorders. Utilising endophenotypes derived from various assessments like neuroimaging can enhance the reliability of research on brain function. Dr. John P. John Professor, Department of Psychiatry Dr. Venkatasubramanian Ganesan Professor, Department of Psychiatry Dr. Jitender Saini Professor, Department of Neuro Imaging & Interventional Radiology Dr Bharath Holla Associate Professor, Department of Psychiatry Dr. Sreeraj V S Associate Professor, Department of Psychiatry Affiliated Labs and Centre ADBS Neuroimaging Centre (ANC) Centre for Brain Mapping (CBM) Translational Psychiatry Lab (TransPsych) Multi-modal Brain Imaging Analysis Lab (MBIAL) Facilities Eye Tracking Functional Near-Infrared Spectroscopy (fNIRS) MRI Scanner Philips Ingenia 3.0T CX MRI EEG Featured Publications Parekh P, Vivek Bhalerao G; ADBS consortium, John JP, Venkatasubramanian G. Sample size requirement for achieving multisite harmonization using structural brain MRI features. Neuroimage. 2022;264:119768. doi:10.1016/j.neuroimage.2022.119768 Lakkireddy SP, Balachander S, Dayalamurthy P, et al. Neurocognition and its association with adverse childhood experiences and familial risk of mental illness. Prog Neuropsychopharmacol Biol Psychiatry. 2022;119:110620. doi:10.1016/j.pnpbp.2022.110620 Bhalerao GV, Parekh P, Saini J, Venkatasubramanian G, John JP; ADBS consortium. Systematic evaluation of the impact of defacing on quality and volumetric assessments on T1-weighted MR-images. J Neuroradiol. 2022;49(3):250-257. doi:10.1016/j.neurad.2021.03.001 Parekh P, Bhalerao GV, Rao R, et al. Protocol for magnetic resonance imaging acquisition, quality assurance, and quality check for the Accelerator program for Discovery in Brain disorders using Stem cells. Int J Methods Psychiatr Res. 2021;30(3):e1871. doi:10.1002/mpr.1871 Holla B, Dayal P, Das A, et al. Transdiagnostic neurocognitive endophenotypes in major psychiatric illness. medRxiv (Cold Spring Harbor Laboratory). February 2020. doi:10.1101/2020.02.14.20022863

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Learn more about upcoming events at the Centre for Brain and Mind - NIMHANS Upcoming Events 4 दिनों तक का आयोजन Brain Bridge: Talks by CBM NIMHANS | Dr Max Lam 12 सित॰ 2026, 5:30 pm – 6:30 pm RSVP Past Events Perspectives of Addiction - Zine Making Workshop शनि, 04 जुल॰ NIMHANS Centre for Well-Being विवरण The Fault in our Cells रवि, 26 अप्रैल The Bangalore Local Why do mental illnesses exist and why do they affect some people but not others ? विवरण Medulina Matu | Prof Raghu Padinjat शुक्र, 06 मार्च Samagata Foundation Medulina Mathu (“brain talks”) is a new series by the Centre for Brain and Mind, NIMHANS, that brings neuroscience out of the lab and into everyday conversation. विवरण Brain Bridge: Talks by CBM NIMHANS | Prof Deepak Srivastava गुरु, 12 फ़र॰ Zoom Webinar विवरण Sci560: Science in the City शनि, 16 नव॰ Science Gallery Bengaluru This weekend scholars from NIMHANS will be at the Science Gallery Bengaluru for a series of programmes focused on mental health. Recordings of the events will be available on the Science Gallery Bengaluru website. विवरण अधिक लोड करें

Genetics and Stem Cell Group Endophenotype Group Clinical Group Psychiatric disorders commonly emerge in young adulthood and significantly impact career choices and lifespan. Early onset of symptoms, usually before age 24, underscores the need for comprehensive support and intervention. The absence of a clear link between genes and observable traits makes treatment plans more complex. The neuropsychiatric disorders we study often have origins in early development, necessitating a shift towards understanding developmental trajectories. How We Work Together Dr Y C Janardhan Reddy Lead Investigator, Obsessive Compulsive Disorder Cohort Dr. Vivek Benegal Lead Investigator, Addiction Cohort Dr Biju Viswanath Lead Investigator, Bipolar Disorder Cohort Dr. PT Sivakumar Co-Investigator, Dementia Cohort Dr. Vijay Kumar K.G. Co-Investigator, Schizophrenia Cohort Dr Jayant Mahadevan Co-Investigator, Addiction Cohort Dr. Preethi V. Reddy Co-Investigator, Bipolar Disorder Cohort Dr. Lekhansh Shukla Co-Investigator, Addiction Cohort Dr. Srinivas Balachander Co-Investigator, Obsessive Compulsive Disorder Cohort Dr Suhas Satish Co-Investigator, Schizophrenia Cohort Dr. Vijaykumar S Harbishettar Co-Investigator, Dementia Cohort Affiliated Labs & Centres Department of Psychiatry, NIMHANS Schizophrenia & Metabolic Clinic Obsessive-Compulsive Disorder Clinic Centre for Addiction Medicine (CAM) Geriatric Clinic Featured Publications Nayok, S.B. et al. (2025) “Gaze fixation stability is a transdiagnostic marker of major psychiatric disorders: A high-density family-based study.” medRxiv, p. 2025.06.23.25330103. Available at: https://doi.org/10.1101/2025.06.23.25330103 . Durbagula, S. et al. (2024) “Genetic insights into male autism spectrum disorder in a small cohort of Indian simplex families: findings from whole exome sequencing,” General Psychiatry, 37(6), p. e101606. Available at: https://doi.org/10.1136/gpsych-2024-101606 . Muthukumaran, M. et al. (2024) “Shared deficits of education, marital and occupational functioning in unaffected siblings of multiple affected families with major psychiatric illness,” Asian Journal of Psychiatry, 101, p. 104216. Available at: https://doi.org/10.1016/j.ajp.2024.104216 . Lakkireddy SP, Balachander S, Dayalamurthy P, et al. Neurocognition and its association with adverse childhood experiences and familial risk of mental illness. Prog Neuropsychopharmacol Biol Psychiatry. 2022;119:110620. doi:10.1016/j.pnpbp.2022.110620 Vinod, P. et al. (2024) “Does Apolipoprotein E polymorphism play a role in familial Alzheimer’s Dementia,” Alzheimer’s & Dementia, 20(S1), p. e087257. Available at: https://doi.org/10.1002/alz.087257 .

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सभी (26) General Pages (19) इवेंट्स (7) "" के लिए परिणाम मिले General Pages (19) Fullscreen Page | CBM NIMHANS Participate in our research | CBM NIMHANS Participate in Our Research Be a part of our groundbreaking research initiatives by volunteering! You can explore the dedicated pages for each research group to learn more about the innovative studies our scientists are conducting. Our research delves into understanding the complexities behind severe psychiatric illnesses. Our studies may involve - ​ non-invasive methods like EEG recordings, where sensors are placed on the scalp to capture brainwave activity MRI brain scans simple measurements of button-press responses or eye movements blood sample which will be used for genetic and stem cell studies ​ For more information, please read the “Information & Consent Forms” (links to the PDF documents in various languages are given below) ​ If you are eager to participate as a research volunteer, you can register by filling out the form below . Once registered, we will reach out to you when a suitable study becomes available. Your involvement plays a crucial role in advancing our understanding of the human brain, and we welcome you to be a part of our exciting journey in pushing the boundaries of scientific exploration. Information and Consent Forms (PDF) Control (Unaffected Persons) Patient Relatives English Kannada Hindi Tamil Telugu Malayalam English Kannada Hindi Tamil Telugu Malayalam English Kannada Hindi Tamil Telugu Malayalam News | CBM NIMHANS In the News 2024-07-24 ‘Understanding how and why people go mad has been a critical aspect of human society’ Dr. Sanjeev Jain, author of Mindscape and Landscape: An Illustrated History of NIMHANS, offered insights into the history of mental health at an event in Bengaluru Know more 2024-07-21 Experts urge sensitive depiction of mental health in films Experts discuss cinema’s impact on mental health at an event in NINMHANS in Bengaluru on Saturday. Know more 2024-03-26 Matters of mind and art The Centre for Brain and Mind at NIMHANS, a research venture launched in 2023, will commemorate World Bipolar Day on March 30 the birthday of the iconic artist Vincent van Gogh, by delving into the captivating fusion of science and art. Know more 2024-03-10 Variations in Bipolar Disorder: Insights from and Treatment Implications in Indian Patients The DBT/Wellcome Trust India welcomed 15 Early Career Fellows this year. This article introduces the research project of Dr. Biju Viswanath, DBT/WT India Alliance Intermediate Fellow in the Clinical and Public Health. Know more 2024-01-21 Pune, now a home to India Science Fest At more than 30 interactive stalls, students can learn about science concepts, including some set up by the industry. The fest also has fun competitions in science photography, science fiction writing, explaining one’s thesis to younger children, with prizes worth Rs 5 lakh. Know more 2023-12-24 NIMHANS-led PARAM research to predict and prevent brain disorders The research will also help the medical fraternity determine the risk factors that contribute to the disorders and the impact of environmental and societal conditions on the development of the human brain. Know more 2023-11-26 Virtual screening of international dementia documentary at NIMHANS fosters... Experts emphasised the critical role of awareness and destigmatisation in addressing the challenges posed by dementia and its contribution to a holistic understanding of dementia and its impact on individuals and communities. Know more 2023-10-10 Mansukh Madaviya inaugurates Centre for Brain and Mind at NIMHANS The Centre for Brain and Mind was launched in collaboration with National Centre for Biological Sciences (NCBS) with the contribution of Rs 100 crore from Rohini Nilekani Philanthropies. Know more 2023-07-04 Rohini Nilekani Centre for Brain and Mind launched at NCBS Bengaluru The centre is an outcome of a ₹100 crore grant to NCBS and NIMHANS for long-term research, and to build capacity for both research and practice in the mental health field Know more Read More सभी देखें इवेंट्स (7) Stories in Motion: Mental Wellness through Art and Narratives by Dr. Ankit Dwivedi 21 July 2024 | 11:30 am 7, 4th Main Rd, Stage 2, Domlur, Bengaluru, Karnataka 560071, India Mental Health & Movies - The Good, The Bad & The Ugly 20 July 2024 | 1:00 pm 7, 4th Main Rd, Stage 2, Domlur, Bengaluru, Karnataka 560071, India "Mindscape and Landscape: An Illustrated History of NIMHANS" by Dr. Sanjeev Jain 17 July 2024 | 10:30 am 178, 5th Main Rd, Indira Nagar 1st Stage, 1st Stage, Indiranagar, Bengaluru, Karnataka 560038, India सभी देखें

सोम, 15 जुल॰ | Bengaluru Coffee, Cinema and Community: Mental Health Redefined समय और स्थान 15 जुल॰ 2024, 9:00 am – 21 जुल॰ 2024, 7:00 pm Bengaluru इवेंट के बारे में This Brain Awareness Week program will bring discussions around mental health to our beautiful city. From cafe book talks to film discussions, from art exhibitions to storytelling workshops - let's talk about mental health, Bengaluru! Scroll down and click "see all" to view the full event schedule, or view full-size poster here अधिक पढ़ें > शेड्यूल 4:00 pm - 11:59 pm 17 दिन 7 घंटे 59 मिनट Registrations Open | Through the Looking Glass: Artistic Perspectives on Mental Health 4:00 pm - 6:00 pm 2 घंटे Book Talk: Mindscape and Landscape: An Illustrated History of NIMHANS by Dr Sanjeev Jain Atta Galatta, Indiranagar 3 और आइटम उपलब्ध हैं सभी देखें यह इवेंट साझा करें

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